Exploring modular allostery via interchangeable regulatory domains

Por Fan, Yifei, Cross, Penelope J., Jameson, Geoffrey B., Parker, Emily J.
Publicado no Proc Natl Acad Sci U S A (2018)

Tyrosine Latching of a Regulatory Gate Affords Allosteric Control of Aromatic Amino Acid Biosynthesis

Por Cross, Penelope J., Dobson, Renwick C. J., Patchett, Mark L., Parker, Emily J.
Publicado em 2011

The Functional Unit of Neisseria meningitidis 3-Deoxy-ᴅ-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric

Por Cross, Penelope J., Heyes, Logan C., Zhang, Shiwen, Nazmi, Ali Reza, Parker, Emily J.
Publicado no PLoS One (2016)

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain

Por Cross, Penelope J., Allison, Timothy M., Dobson, Renwick C. J., Jameson, Geoffrey B., Parker, Emily J.
Publicado em 2013

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals

Por Parthasarathy, Anutthaman, Cross, Penelope J., Dobson, Renwick C. J., Adams, Lily E., Savka, Michael A., Hudson, André O.
Publicado no Front Mol Biosci (2018)

Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine

Por Cross, Penelope J, Pietersma, Amy L, Allison, Timothy M, Wilson-Coutts, Sarah M, Cochrane, Fiona C, Parker, Emily J
Publicado em 2013

First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer

Por Arturo, Emilia C., Gupta, Kushol, Héroux, Annie, Stith, Linda, Cross, Penelope J., Parker, Emily J., Loll, Patrick J., Jaffe, Eileen K.
Publicado no Proc Natl Acad Sci U S A (2016)

Structure–function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

Por Crowther, Jennifer M., Cross, Penelope J., Oliver, Michael R., Leeman, Mary M., Bartl, Austin J., Weatherhead, Anthony W., North, Rachel A., Donovan, Katherine A., Griffin, Michael D. W., Suzuki, Hironori, Hudson, André O., Kasanmascheff, Müge, Dobson, Renwick C. J.
Publicado no J Biol Chem (2019)