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Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids

Because of their special organization, multifunctional enzymes play crucial roles in improving the performance of metabolic pathways. For example, the bacterium Prevotella nigrescens contains a distinctive bifunctional protein comprising a 3-deoxy-d-arabino heptulosonate-7-phosphate synthase (DAH7PS...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bai, Yu, Lang, Eric J. M., Nazmi, Ali Reza, Parker, Emily J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442060/
https://ncbi.nlm.nih.gov/pubmed/30670586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005220
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