LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance

Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos and are critical regulators of lymphoid lineage fat...

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Detalles Bibliográficos
Autores principales: Lee, Sung-Uk, Maeda, Manami, Ishikawa, Yuichi, Li, Sierra Min, Wilson, Anne, Jubb, Adrian M., Sakurai, Nagisa, Weng, Lihong, Fiorini, Emma, Radtke, Freddy, Yan, Minhong, MacDonald, H. Robson, Chen, Ching-Cheng, Maeda, Takahiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2013
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567339/
https://ncbi.nlm.nih.gov/pubmed/23134786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-418103
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