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The LRF transcription factor regulates mature B cell development and the germinal center response in mice
B cells play a central role in immune system function. Deregulation of normal B cell maturation can lead to the development of autoimmune syndromes as well as B cell malignancies. Elucidation of the molecular features of normal B cell development is important for the development of new target therap...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223838/ https://ncbi.nlm.nih.gov/pubmed/21646720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45682 |
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