LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis

GATA-1-dependent transcription is essential for erythroid differentiation and maturation. Suppression of programmed cell death is also thought to be critical for this process; however, the link between these two features of erythropoiesis has remained elusive. Here, we show that the POZ-Krüppel fami...

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Detalhes bibliográficos
Main Authors: Maeda, Takahiro, Ito, Keisuke, Merghoub, Taha, Poliseno, Laura, Hobbs, Robin M., Wang, Guocan, Dong, Lin, Maeda, Manami, Dore, Louis C., Zelent, Arthur, Luzzatto, Lucio, Teruya-Feldstein, Julie, Weiss, Mitchell J., Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134301/
https://ncbi.nlm.nih.gov/pubmed/19853566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.09.005
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