LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance

Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos and are critical regulators of lymphoid lineage fat...

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Dettagli Bibliografici
Autori principali: Lee, Sung-Uk, Maeda, Manami, Ishikawa, Yuichi, Li, Sierra Min, Wilson, Anne, Jubb, Adrian M., Sakurai, Nagisa, Weng, Lihong, Fiorini, Emma, Radtke, Freddy, Yan, Minhong, MacDonald, H. Robson, Chen, Ching-Cheng, Maeda, Takahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567339/
https://ncbi.nlm.nih.gov/pubmed/23134786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-418103
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