LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance

Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos and are critical regulators of lymphoid lineage fat...

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Detalhes bibliográficos
Main Authors: Lee, Sung-Uk, Maeda, Manami, Ishikawa, Yuichi, Li, Sierra Min, Wilson, Anne, Jubb, Adrian M., Sakurai, Nagisa, Weng, Lihong, Fiorini, Emma, Radtke, Freddy, Yan, Minhong, MacDonald, H. Robson, Chen, Ching-Cheng, Maeda, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567339/
https://ncbi.nlm.nih.gov/pubmed/23134786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-418103
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