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The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation

T helper (Th) cells are critical for defenses against infection and recognize peptides bound to Class II Major Histocompatibility Complex (MHC-II) molecules. Although transcription factors have been identified that direct helper cells into specific effector fates, whether a ‘master’ regulator contro...

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Hlavní autoři: Carpenter, Andrea C., Grainger, John R., Xiong, Yumei, Kanno, Yuka, Chu, H. Hamlet, Wang, Lie, Naik, Shruti, dos Santos, Liliane, Wei, Lai, Jenkins, Marc K., O’Shea, John J., Belkaid, Yasmine, Bosselut, Rémy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050670/
https://ncbi.nlm.nih.gov/pubmed/23041065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.019
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