The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation

T helper (Th) cells are critical for defenses against infection and recognize peptides bound to Class II Major Histocompatibility Complex (MHC-II) molecules. Although transcription factors have been identified that direct helper cells into specific effector fates, whether a ‘master’ regulator contro...

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Autors principals: Carpenter, Andrea C., Grainger, John R., Xiong, Yumei, Kanno, Yuka, Chu, H. Hamlet, Wang, Lie, Naik, Shruti, dos Santos, Liliane, Wei, Lai, Jenkins, Marc K., O’Shea, John J., Belkaid, Yasmine, Bosselut, Rémy
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050670/
https://ncbi.nlm.nih.gov/pubmed/23041065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.019
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