LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance

Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos and are critical regulators of lymphoid lineage fat...

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Détails bibliographiques
Auteurs principaux: Lee, Sung-Uk, Maeda, Manami, Ishikawa, Yuichi, Li, Sierra Min, Wilson, Anne, Jubb, Adrian M., Sakurai, Nagisa, Weng, Lihong, Fiorini, Emma, Radtke, Freddy, Yan, Minhong, MacDonald, H. Robson, Chen, Ching-Cheng, Maeda, Takahiro
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Hematopoiesis and Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567339/
https://ncbi.nlm.nih.gov/pubmed/23134786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-418103
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