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20S-Hydroxyvitamin D(3), Noncalcemic Product of CYP11A1 Action on Vitamin D(3), Exhibits Potent Antifibrogenic Activity in Vivo
CONTEXT: There is no effective treatment for systemic sclerosis and related fibrosing diseases. Recently the action of CYP11A1 on vitamin D(3) was shown to produce biologically active 20S-hydroxyvitamin D [20(OH)D(3)] and 20,23(OH)(2)D(3), 20,22(OH)(2)D(3), and 17,20,23(OH)(3)D(3). OBJECTIVES: Becau...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Endocrine Society
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565109/ https://ncbi.nlm.nih.gov/pubmed/23295467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-3074 |
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