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Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4
20S-Hydroxyvitamin D3 [20(OH)D3] is the biologically active major product of the action of CYP11A1 on vitamin D3 and is present in human plasma. 20(OH)D3 displays similar therapeutic properties to 1,25-dihydroxyvitamin D3 [1,25(OH)(2)D3], but without causing hypercalcaemia and therefore has potentia...
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| Published in: | J Steroid Biochem Mol Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821771/ https://ncbi.nlm.nih.gov/pubmed/26970587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.03.014 |
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