Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity

20-Hydroxyvitamin D(3) (20(OH)D(3)), the major product of CYP11A1 action on vitamin D(3), is biologically active and is produced in vivo. As well as potentially having important physiological actions, it is of interest as a therapeutic agent due to its lack of calcemic activity. In the current study...

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Détails bibliographiques
Auteurs principaux: Tieu, Elaine W., Tang, Edith K. Y., Chen, Jianjun, Li, Wei, Nguyen, Minh N., Janjetovic, Zorica, Slominski, Andrzej, Tuckey, Robert C.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501553/
https://ncbi.nlm.nih.gov/pubmed/23041230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.09.032
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