Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity

20-Hydroxyvitamin D(3) (20(OH)D(3)), the major product of CYP11A1 action on vitamin D(3), is biologically active and is produced in vivo. As well as potentially having important physiological actions, it is of interest as a therapeutic agent due to its lack of calcemic activity. In the current study...

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Detalhes bibliográficos
Main Authors: Tieu, Elaine W., Tang, Edith K. Y., Chen, Jianjun, Li, Wei, Nguyen, Minh N., Janjetovic, Zorica, Slominski, Andrzej, Tuckey, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501553/
https://ncbi.nlm.nih.gov/pubmed/23041230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.09.032
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