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Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ
Previous studies showed that noncalcemic 20(OH)D(3), a product of CYP11A1 action on vitamin D(3), has antifibrotic activity in human dermal fibroblasts and in a bleomycin mouse model of scleroderma. In this study, we tested the role of retinoic acid-related orphan receptor γ (RORγ), which is express...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Endocrinology |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7717072/ https://ncbi.nlm.nih.gov/pubmed/33107570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa198 |
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