Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway

Mutations in the NF1 tumor suppressor gene cause Neurofibromatosis type 1 (NF1). Neurofibromin, the protein product of NF1, functions as a negative regulator of Ras activity. Some NF1 patients develop cardiovascular disease, which represents an underrecognized disease complication and contributes to...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Stansfield, Brian K., Bessler, Waylan K., Mali, Raghuveer, Mund, Julie A., Downing, Brandon, Li, Fang, Sarchet, Kara N., DiStasi, Matthew R., Conway, Simon J., Kapur, Reuben, Ingram, David A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561913/
https://ncbi.nlm.nih.gov/pubmed/23197650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds502
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars