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Ras-Mek-Erk Signaling Regulates Nf1 Heterozygous Neointima Formation
Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor-suppressor gene, which encodes neurofibromin, a negative regulator of diverse Ras signaling cascades. Arterial stenosis is a nonneoplastic manifestation of NF1 that predisposes some patients to debilitating morbidity and sudden d...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873499/ https://ncbi.nlm.nih.gov/pubmed/24211110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.022 |
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