Ras-Mek-Erk Signaling Regulates Nf1 Heterozygous Neointima Formation

Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor-suppressor gene, which encodes neurofibromin, a negative regulator of diverse Ras signaling cascades. Arterial stenosis is a nonneoplastic manifestation of NF1 that predisposes some patients to debilitating morbidity and sudden d...

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Bibliografische gegevens
Hoofdauteurs: Stansfield, Brian K., Bessler, Waylan K., Mali, Raghuveer, Mund, Julie A., Downing, Brandon D., Kapur, Reuben, Ingram, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2014
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Short Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873499/
https://ncbi.nlm.nih.gov/pubmed/24211110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.022
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