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Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis
Protease activated receptor-2 (PAR(2)) is one of four G-protein coupled receptors (GPCRs) that can be activated by exogenous or endogenous proteases, which cleave the extracellular amino-terminus to expose a tethered ligand and subsequent G-protein signaling. Alternatively, PAR(2) can be activated b...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556274/ https://ncbi.nlm.nih.gov/pubmed/22994402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300300q |
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