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Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis
Protease activated receptor-2 (PAR(2)) is one of four G-protein coupled receptors (GPCRs) that can be activated by exogenous or endogenous proteases, which cleave the extracellular amino-terminus to expose a tethered ligand and subsequent G-protein signaling. Alternatively, PAR(2) can be activated b...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556274/ https://ncbi.nlm.nih.gov/pubmed/22994402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300300q |
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