IL-7 signaling must be intermittent, not continuous, during CD8 T cell homeostasis to promote cell survival instead of cell death

Lignende værker

• Lck availability during thymic selection determines the recognition specificity of the T cell repertoire
  af: Van Laethem, François, et al.
  Udgivet: (2013)
• Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells
  af: Tai, Xuguang, et al.
  Udgivet: (2012)
• Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors
  af: Kimura, Motoko Y, et al.
  Udgivet: (2016)
• Foxp3 transcription factor is pro-apoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals
  af: Tai, Xuguang, et al.
  Udgivet: (2013)
• Let-7 miRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function
  af: Pobezinsky, Leonid A., et al.
  Udgivet: (2015)