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Predicting Enhanced Cell Killing through PARP Inhibition

PARP inhibitors show promise as combination and single agents in cancer chemotherapy. Here, we evaluate results obtained with mouse fibroblasts and the common laboratory PARP inhibitor, 4-amino-1,8-naphthalimide (4-AN), and analyze the potential for enhanced cytotoxicity following the combination of...

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Detaylı Bibliyografya
Asıl Yazarlar: Horton, Julie K., Wilson, Samuel H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552016/
https://ncbi.nlm.nih.gov/pubmed/23193155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0512
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