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Predicting Enhanced Cell Killing through PARP Inhibition

PARP inhibitors show promise as combination and single agents in cancer chemotherapy. Here, we evaluate results obtained with mouse fibroblasts and the common laboratory PARP inhibitor, 4-amino-1,8-naphthalimide (4-AN), and analyze the potential for enhanced cytotoxicity following the combination of...

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書誌詳細
主要な著者: Horton, Julie K., Wilson, Samuel H.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552016/
https://ncbi.nlm.nih.gov/pubmed/23193155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0512
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