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Predicting Enhanced Cell Killing through PARP Inhibition
PARP inhibitors show promise as combination and single agents in cancer chemotherapy. Here, we evaluate results obtained with mouse fibroblasts and the common laboratory PARP inhibitor, 4-amino-1,8-naphthalimide (4-AN), and analyze the potential for enhanced cytotoxicity following the combination of...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552016/ https://ncbi.nlm.nih.gov/pubmed/23193155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0512 |
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