Cargando...
Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition
Inhibition of PARP activity results in extreme sensitization to MMS-induced cell killing in cultured mouse fibroblasts. In these MMS-treated cells, PARP inhibition is accompanied by an accumulation of S-phase cells that requires signaling by the checkpoint kinase ATR (Horton et al. (2005) J. Biol. C...
Gardado en:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585487/ https://ncbi.nlm.nih.gov/pubmed/18691676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.07.006 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|