Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching

DNA double-strand breaks (DSBs) are byproducts of normal cellular metabolism and obligate intermediates in antigen receptor diversification reactions. These lesions are potentially dangerous because they can lead to deletion of genetic material or chromosome translocation. The chromatin-binding prot...

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Detalhes bibliográficos
Main Authors: Bothmer, Anne, Rommel, Philipp C., Gazumyan, Anna, Polato, Federica, Reczek, Colleen R., Muellenbeck, Matthias F., Schaetzlein, Sonja, Edelmann, Winfried, Chen, Phang-Lang, Brosh, Robert M., Casellas, Rafael, Ludwig, Thomas, Baer, Richard, Nussenzweig, André, Nussenzweig, Michel C., Robbiani, Davide F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549709/
https://ncbi.nlm.nih.gov/pubmed/23254285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121975
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