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Menin as a Hub Controlling Mixed Lineage Leukemia

Mixed lineage leukemia (MLL) fusion protein (FP)-induced acute leukemia is highly aggressive and often refractory to therapy. Recent progress in the field has unraveled novel mechanisms and targets to combat this disease. Menin, a nuclear protein, interacts with wild-type (WT) MLL, MLL-FPs and other...

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Hlavní autoři: Thiel, Austin, Huang, Jing, Lei, Ming, Hua, Xianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536020/
https://ncbi.nlm.nih.gov/pubmed/22829075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200007
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