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The same pocket in menin binds both MLL and JunD, but oppositely regulates transcription
Menin is a tumor suppressor protein whose loss or inactivation causes multiple endocrine neoplasia type 1 (MEN1), a hereditary autosomal dominant tumor syndrome characterized by tumorigenesis in multiple endocrine organs(1). Menin interacts with a multitude of proteins and involves in a variety of c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983792/ https://ncbi.nlm.nih.gov/pubmed/22327296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10806 |
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