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The same pocket in menin binds both MLL and JunD, but oppositely regulates transcription

Menin is a tumor suppressor protein whose loss or inactivation causes multiple endocrine neoplasia type 1 (MEN1), a hereditary autosomal dominant tumor syndrome characterized by tumorigenesis in multiple endocrine organs(1). Menin interacts with a multitude of proteins and involves in a variety of c...

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Hlavní autoři: Huang, Jing, Gurung, Buddha, Wan, Bingbing, Wan, Ke, Hua, Xianxin, Lei, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983792/
https://ncbi.nlm.nih.gov/pubmed/22327296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10806
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