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Menin and JunD regulate gastrin gene expression through proximal DNA elements

Mutations in the MEN1 gene correlate with multiple endocrine neoplasia I (MEN1). Gastrinomas are the most malignant of the neuroendocrine tumors associated with MEN1. Because menin and JunD proteins interact, we examined whether JunD binds to and regulates the gastrin gene promoter. Both menin and J...

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Detalles Bibliográficos
Main Authors: Mensah-Osman, Edith J., Veniaminova, Natalia A., Merchant, Juanita L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220327/
https://ncbi.nlm.nih.gov/pubmed/21852362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00160.2011
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