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Menin: a scaffold protein that controls gene expression and cell signaling
The protein menin is encoded by the MEN1 gene, which is mutated in patients with multiple endocrine neoplasia type 1 (MEN1) syndrome. Although menin acts as a tumor suppressor in endocrine organs, it is required for leukemic transformation in mouse models. Menin possesses these dichotomous functions...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741089/ https://ncbi.nlm.nih.gov/pubmed/23850066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.05.005 |
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