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Menin as a Hub Controlling Mixed Lineage Leukemia
Mixed lineage leukemia (MLL) fusion protein (FP)-induced acute leukemia is highly aggressive and often refractory to therapy. Recent progress in the field has unraveled novel mechanisms and targets to combat this disease. Menin, a nuclear protein, interacts with wild-type (WT) MLL, MLL-FPs and other...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536020/ https://ncbi.nlm.nih.gov/pubmed/22829075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200007 |
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