SCG10 is a JNK target in the axonal degeneration pathway

Axons actively self-destruct following genetic, mechanical, metabolic, and toxic insults, but the mechanism of axonal degeneration is poorly understood. The JNK pathway promotes axonal degeneration shortly after axonal injury, hours before irreversible axon fragmentation ensues. Inhibition of JNK ac...

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Detalhes bibliográficos
Main Authors: Shin, Jung Eun, Miller, Bradley R., Babetto, Elisabetta, Cho, Yongcheol, Sasaki, Yo, Qayum, Shehzad, Russler, Emilie V., Cavalli, Valeria, Milbrandt, Jeffrey, DiAntonio, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535671/
https://ncbi.nlm.nih.gov/pubmed/23188802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216204109
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