A carregar...
A DLK-dependent axon self-destruction program promotes Wallerian degeneration
Axon degeneration underlies many common neurological disorders, but the signaling pathways that orchestrate axon degeneration are unknown. We demonstrate that the dual leucine kinase (DLK) promotes degeneration of severed axons in Drosophila and mice, and its target JNK promotes degeneration locally...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696160/ https://ncbi.nlm.nih.gov/pubmed/19287387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2290 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|