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The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction

Axon degeneration is an evolutionarily conserved process that drives the loss of damaged axons and is an early event in many neurological disorders, and so it is important to identify the molecular constituents of this poorly understood mechanism. Here we demonstrate that the Phr1 E3 ubiquitin ligas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Babetto, Elisabetta, Beirowski, Bogdan, Russler, Emilie, Milbrandt, Jeffrey, DiAntonio, Aaron
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671584/
https://ncbi.nlm.nih.gov/pubmed/23665224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.013
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