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Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration
Here we demonstrate that the dual leucine zipper kinase (DLK) promotes robust regeneration of peripheral axons following nerve injury in mice. Peripheral axon regeneration is accelerated by prior injury, however DLK KO neurons do not respond to a preconditioning lesion with enhanced regeneration in...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383631/ https://ncbi.nlm.nih.gov/pubmed/22726832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.04.028 |
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