Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration

Here we demonstrate that the dual leucine zipper kinase (DLK) promotes robust regeneration of peripheral axons following nerve injury in mice. Peripheral axon regeneration is accelerated by prior injury, however DLK KO neurons do not respond to a preconditioning lesion with enhanced regeneration in...

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Библиографические подробности
Главные авторы: Shin, Jung Eun, Cho, Yongcheol, Beirowski, Bogdan, Milbrandt, Jeffrey, Cavalli, Valeria, DiAntonio, Aaron
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383631/
https://ncbi.nlm.nih.gov/pubmed/22726832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.04.028
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