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Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration

Here we demonstrate that the dual leucine zipper kinase (DLK) promotes robust regeneration of peripheral axons following nerve injury in mice. Peripheral axon regeneration is accelerated by prior injury, however DLK KO neurons do not respond to a preconditioning lesion with enhanced regeneration in...

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Bibliografiske detaljer
Main Authors: Shin, Jung Eun, Cho, Yongcheol, Beirowski, Bogdan, Milbrandt, Jeffrey, Cavalli, Valeria, DiAntonio, Aaron
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383631/
https://ncbi.nlm.nih.gov/pubmed/22726832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.04.028
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