Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration

Here we demonstrate that the dual leucine zipper kinase (DLK) promotes robust regeneration of peripheral axons following nerve injury in mice. Peripheral axon regeneration is accelerated by prior injury, however DLK KO neurons do not respond to a preconditioning lesion with enhanced regeneration in...

Full description

Saved in:
Bibliographic Details
Main Authors: Shin, Jung Eun, Cho, Yongcheol, Beirowski, Bogdan, Milbrandt, Jeffrey, Cavalli, Valeria, DiAntonio, Aaron
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383631/
https://ncbi.nlm.nih.gov/pubmed/22726832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.04.028
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items