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Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration

Injured peripheral neurons successfully activate a pro-regenerative program to enable axon regeneration and functional recovery. The microtubule-dependent retrograde transport of injury signals from the lesion site in the axon back to the cell soma stimulates the increased growth capacity of injured...

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Publicat a:J Biol Chem
Autors principals: Song, Wenjun, Cho, Yongcheol, Watt, Dana, Cavalli, Valeria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505541/
https://ncbi.nlm.nih.gov/pubmed/25911101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622753
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