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Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration
Injured peripheral neurons successfully activate a pro-regenerative program to enable axon regeneration and functional recovery. The microtubule-dependent retrograde transport of injury signals from the lesion site in the axon back to the cell soma stimulates the increased growth capacity of injured...
Bewaard in:
Gepubliceerd in: | J Biol Chem |
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Hoofdauteurs: | , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2015
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505541/ https://ncbi.nlm.nih.gov/pubmed/25911101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622753 |
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