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Neuronal Activity and Secreted Amyloid β Lead to Altered Amyloid β Precursor Protein and Presenilin 1 Interactions
Deposition of amyloid β (Aβ) containing plaques in the brain is one of the neuropathological hallmarks of Alzheimer's disease (AD). It has been suggested that modulation of neuronal activity may alter Aβ production in the brain. We postulate that these changes in Aβ production are due to change...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534898/ https://ncbi.nlm.nih.gov/pubmed/23064434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.10.002 |
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