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Neuronal Activity and Secreted Amyloid β Lead to Altered Amyloid β Precursor Protein and Presenilin 1 Interactions

Deposition of amyloid β (Aβ) containing plaques in the brain is one of the neuropathological hallmarks of Alzheimer's disease (AD). It has been suggested that modulation of neuronal activity may alter Aβ production in the brain. We postulate that these changes in Aβ production are due to change...

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書誌詳細
主要な著者: Li, Xuejing, Uemura, Kengo, Hashimoto, Tadafumi, Arimon, Muriel, Lill, Christina M., Palazzolo, Isabella, Krainc, Dimitri, Hyman, Bradley T., Berezovska, Oksana
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534898/
https://ncbi.nlm.nih.gov/pubmed/23064434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.10.002
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