Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma

The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [(3)H]caspofungin to healthy men, plasma, urine, and feces were collected over 27 days in study A (n = 6) and plasma was collected over 26 weeks in stud...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Stone, Julie A., Xu, Xin, Winchell, Gregory A., Deutsch, Paul J., Pearson, Paul G., Migoya, Elizabeth M., Mistry, Goutam C., Xi, Liwen, Miller, Alisha, Sandhu, Punam, Singh, Romi, deLuna, Florencia, Dilzer, Stacy C., Lasseter, Kenneth C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353127/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.815-823.2004
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