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Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [(3)H]caspofungin to healthy men, plasma, urine, and feces were collected over 27 days in study A (n = 6) and plasma was collected over 26 weeks in stud...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC353127/ https://ncbi.nlm.nih.gov/pubmed/14982770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.815-823.2004 |
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