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Addition of Caspofungin to Fluconazole Does Not Improve Outcome in Murine Candidiasis

Caspofungin is a potent antifungal inhibiting glucan synthesis in Candida species. However, caspofungin is not 100% curative in candidiasis. Therefore, we evaluated combinations of fluconazole with caspofungin for murine candidemia. We could not show any benefit of combined therapy over individual a...

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Detalhes bibliográficos
Principais autores: Graybill, John R., Bocanegra, Rosie, Najvar, Laura K., Hernandez, Steve, Larsen, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161841/
https://ncbi.nlm.nih.gov/pubmed/12821503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.7.2373-2375.2003
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