Addition of Caspofungin to Fluconazole Does Not Improve Outcome in Murine Candidiasis

Caspofungin is a potent antifungal inhibiting glucan synthesis in Candida species. However, caspofungin is not 100% curative in candidiasis. Therefore, we evaluated combinations of fluconazole with caspofungin for murine candidemia. We could not show any benefit of combined therapy over individual a...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Graybill, John R., Bocanegra, Rosie, Najvar, Laura K., Hernandez, Steve, Larsen, Robert A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821503/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2373-2375.2003
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