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Centrally Acting Oximes in Reactivation of Tabun-Phosphoramidated AChE
Organophosphates (OP) inhibit acetylcholinesterase (AChE, E.C.3.1.1.7), both in peripheral tissues and central nervous system (CNS), causing adverse and sometimes fatal effects due to the accumulation of neurotransmitter acetylcholine (ACh). The currently used therapy, focusing on the reactivation o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530643/ https://ncbi.nlm.nih.gov/pubmed/22960624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.08.019 |
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