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Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure

In the development of antidotal therapy for treatment of organophosphate exposure from pesticides used in agriculture and nerve agents insidiously employed in terrorism, the alkylpyridinium aldoximes have received primary attention since their early development by I. B. Wilson in the 1950s. Yet thes...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Principais autores: Sit, Rakesh K., Kovarik, Zrinka, Maček Hrvat, Nikolina, Žunec, Suzana, Green, Carol, Fokin, Valery V., Sharpless, K. Barry, Radić, Zoran, Taylor, Palmer
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223194/
https://ncbi.nlm.nih.gov/pubmed/30190337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.249383
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