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HI-6 assisted Catalytic Scavenging of VX by Acetylcholinesterase Choline Binding Site Mutants
The high toxicity of organophosphorus compounds originates from covalent inhibition of acetylcholinesterase (AChE), an essential enzyme in cholinergic neurotransmission. Poisonings that lead to life-threatening toxic manifestations require immediate treatment that combines administration of antichol...
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| Pubblicato in: | Chem Biol Interact |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061595/ https://ncbi.nlm.nih.gov/pubmed/27083141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.04.023 |
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