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Phospholipase Cγ2 plays a role in T-cell receptor signal transduction and T-cell selection()
One of the important signaling events following T-cell receptor (TCR) engagement is activation of phospholipase Cγ (PLCγ). PLCγ has two isoforms, PLCγ1 and PLCγ2. It is known that PLCγ1 is important for TCR signaling and TCR-mediated T-cell selection and functions whereas PLCγ2 is critical for B-cel...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528184/ https://ncbi.nlm.nih.gov/pubmed/22837484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103458 |
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