Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development

Pre-T cell receptor (TCR) signaling is required for pre-T cell survival, proliferation, and differentiation from the CD4 and CD8 double negative (DN) to the double positive (DP) stage. However, the pre-TCR signal transduction pathway is not fully understood and the signaling molecules involved have...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Fu, Guoping, Yu, Mei, Chen, Yuhong, Zheng, Yongwei, Zhu, Wen, Newman, Debra K., Wang, Demin, Wen, Renren
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559087/
https://ncbi.nlm.nih.gov/pubmed/27759161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646522
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