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Phospholipase Cγ2 plays a role in T-cell receptor signal transduction and T-cell selection()

One of the important signaling events following T-cell receptor (TCR) engagement is activation of phospholipase Cγ (PLCγ). PLCγ has two isoforms, PLCγ1 and PLCγ2. It is known that PLCγ1 is important for TCR signaling and TCR-mediated T-cell selection and functions whereas PLCγ2 is critical for B-cel...

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Bibliografische gegevens
Hoofdauteurs: Fu, Guoping, Chen, Yuhong, Schuman, James, Wang, Demin, Wen, Renren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528184/
https://ncbi.nlm.nih.gov/pubmed/22837484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103458
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