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An important role of phospholipase Cγ1 in pre-B-cell development and allelic exclusion
Phospholipase Cγ1 (PLCγ1) has been reported to be expressed predominantly in T cells and to play an important role in T-cell receptor signaling. Here we show that PLCγ1 is expressed throughout B-cell development, with high expression in B-cell progenitors, and is involved in pre-B-cell receptor (pre...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524341/ https://ncbi.nlm.nih.gov/pubmed/15372077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600405 |
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