An important role of phospholipase Cγ1 in pre-B-cell development and allelic exclusion

Phospholipase Cγ1 (PLCγ1) has been reported to be expressed predominantly in T cells and to play an important role in T-cell receptor signaling. Here we show that PLCγ1 is expressed throughout B-cell development, with high expression in B-cell progenitors, and is involved in pre-B-cell receptor (pre...

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Main Authors: Wen, Renren, Chen, Yuhong, Schuman, James, Fu, Guoping, Yang, Shoua, Zhang, Weiguo, Newman, Debra K, Wang, Demin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC524341/
https://ncbi.nlm.nih.gov/pubmed/15372077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600405
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